2025-03-27
AACR 2025 | Transcenta to Debut Preclinical Data of a Novel FGFR2b-targeting ADC
PRINCETON, N.J. and SUZHOU, China, March 27, 2025 -- Transcenta Holding Limited ("Transcenta") (HKEX: 06628), a global clinical stage biopharmaceutical company with fully-integrated capabilities in discovery, research, development and manufacturing of antibody-based therapeutics, announced that it will debut the preclinical data of a novel FGFR2b-targeting ADC as poster presentation at the AACR Annual Meeting to be held in Chicago, USA, from April 25-30, 2025. This ADC, conjugated with a topoisomerase I inhibitor payload using glycosyltransferase-mediated site-specific conjugation, demonstrated significantly enhanced anti-tumor activity compared to MMAE-based ADCs in preclinical gastric and colorectal tumor models.